Potent insulinotropic hormone synthesized by duodenal K-cells. High affinity GIP receptor agonist (EC50 = 0.81 nM) that inhibits gastric acid secretion and stimulates pancreatic insulin release in response to glucose. Also affects lipid metabolism and displays mitogenic and antiapoptotic effects in pancreatic β-cells.

100040-31-1

C226H338N60O66S

4983.6

GIP (human);抑胃肽;GIP, human

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years