产品描述
MHP 133 is a drug with multiple CNS targets(AChE with Ki of 69 μM).
体外活性
MHP-133 exhibits this nicotinic-like activity in the cell line. MHP-133 produces a bi-phasic effect on slice survival, particularly in the dentate gyrus and the CA1 regions[1].
体内活性
MHP-133 (50, 100, or 200 μg/kg, i.p.) enhances acquisition of the task and increases task accuracy In rats, elicits significant improvements in task accuracies during sessions initiated 10 min after dosing[1].
Cas No.
147340-43-0
分子式
C17H20ClN5O3
分子量
377.83
别名
MHP 133
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years