Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.

348086-66-8

C35H44N4O9

664.756

Z-LLE-AMC

DMSO:50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years