N-piperidine Ibrutinib HCl, the hydrochloride salt of N-piperidine Ibrutinib, is an intermediate used in the synthesis of BTK-targeted PROTACs such as SJF620 (DC50 of 7.9 nM for degrading BTK). As an Ibrutinib derivative, N-piperidine Ibrutinib also shows potent BTK inhibitory activity with IC50s of 51.0 and 30.7 nM for inhibiting BTK (WT) and BTK (C481S), respectively.

纯度：≥98%

CAS：2231747-18-3