AF40431 is the first reported small-molecule ligand of sortilin (IC50: 4.4 μM; Kd: 0.7 μM). AF40431 is bound in the neurotensin-binding site of sortilin.

181125-92-8

C17H21NO5

319.35

AF40431

DMSO:25 mg/mL (78.28 mM),ultrasonic and adjust pH to 1 with TFA
Powder: -20°C for 3 years
In solvent: -80°C for 2 years