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RCTR1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RCTR1图片
CAS NO:2095607-49-9
包装:1 mg
市场价:-1元

产品介绍

产品描述

Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1It has been found in human spleen and bone marrow.2RCTR1 is produced via lipoxygenase-mediated oxidation of DHA to 7(S)-8-epoxy-17(S)-HDHA, which is conjugated to glutathione.1,2,3RCTR1 (10 nM) increases phagocytosis ofE. colior apoptotic neutrophils in isolated human monocyte-derived macrophages.2It decreases chemotaxis induced by leukotriene B4in isolated human neutrophils when used at a concentration of 10 nM. RCTR1 (1 and 10 nM) accelerates tissue regeneration in planaria. Intraperitoneal administration of RCTR1 (100 ng/animal) shortens the inflammatory resolution period and decreases inflammatory exudate neutrophil infiltration in a mouse model ofE. coli-induced peritonitis.

Cas No.

2095607-49-9

分子式

C32H47N3O10S

分子量

665.79

别名

RCTR1

储存和溶解度

Ethanol:>0.5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years