VU 0364439是一种mGlu4阳性变构调节剂，EC50为19.8 nM。

VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).

VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63% remaining) than RLM (2% remaining). [1]

1246086-78-1

C18H13Cl2N3O3S

422.29

VU 0364439

H2O:<1 mgml
DMSO:79 mg/mL (187.1 mM)
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years