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AZD3458
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AZD3458图片
CAS NO:2132961-46-5
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品介绍

产品描述

AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ with pIC50s of 9.1, 5.1,<4.5, and 6.5 , respectively).

体内活性

AZD3458 (Compound 15) is a potent and remarkably selective PI3Kγ inhibitor with ADME properties suitable for oral administration.?Compound 15 was advanced into in vivo studies showing dose-dependent inhibition of LPS-induced airway neutrophilia in rats when administered orally.

Cas No.

2132961-46-5

分子式

C20H23N3O4S2

分子量

433.54

别名

AZD3458

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years