Parsaclisib 是有效的、选择性的、具有口服活性的PI3Kδ抑制剂，其 IC50=1 nM。它相对于其他 PI3K I 类同工型的选择性约为 20000 倍。它可用于复发或难治性 B 细胞恶性肿瘤的研究。
产品描述
Parsaclisib is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)
体外活性
Parsaclisib displays significant activity with IC50 values ranging from 0.2 to 2 nM in B and T cell proliferation aaasys.?Parsaclisib inhibits proliferation of several DLBCL and MCL cell lines in vitro (EC50
Cas No.
1426698-88-5
分子式
C20H22ClFN6O2
分子量
432.88
别名
INCB050465;Parsaclisib
储存和溶解度
DMSO:122 mg/mL (281.83 mM,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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