CAS NO: | 122405-33-8 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
Etoposide phosphate disodium (BMY-40481 disodium) is a highly potent anti-cancer chemotherapy agent and a specific topoisomerase II inhibitor to prevent re-ligation of DNA strands. Etoposide phosphate disodium is the phosphate ester prodrug of etoposide and is considered as active equivalent to Etoposide. Etoposide phosphate disodium induces cell cycle arrest, apoptosis, and autophagy. References: [1]. Witterland AH, et al. Etoposide phosphate, the water soluble prodrug of etoposide. Pharm World Sci. 1996 Oct;18(5):163-70.
[2]. Cui D, et al. FBXW7 Confers Radiation Survival by Targeting p53 for Degradation.Cell Rep. 2020 Jan 14;30(2):497-509.e4.
[3]. Bregman CL, et al. Etoposide- and BMY-40481-induced sensory neuropathy in mice.Toxicol Pathol. 1994 Sep-Oct;22(5):528-35.
[4]. SUMMARY OF PRODUCT CHARACTERISTICS
纯度:≥98%
CAS:122405-33-8