您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > CMP-5
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
CMP-5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CMP-5图片
CAS NO:880813-42-3
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

CMP-5 (PRMT5-IN-5) is a first-in-class and specific PRMT5 inhibitor with anticancer (B-cell lymphomas) and immunomodulatory activity. It displays no activity against other type I (PRMT1 and PRMT4) and type II (PRMT7) enzymes. CMP-5 blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells. Inhibition of PRMT5 leads to lost recruitment of a PRMT5/p65/HDAC3-repressive complex on the miR96 promoter, restored miR96 expression, and PRMT5 downregulation.

纯度:≥98%

CAS:880813-42-3