Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].

2446474-09-3

C21H29ClN4O7

484.93

E3ligaseLigand-LinkerConjugates30hydrochloride;Cereblon Ligand-Linker Conjugates 5 hydrochloride;Pomalidomide-PEG3-C2-NH2 hydrochloride;Pomalidomide-PEG3-C2-NH2 hydrochloride

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years