PomalIDOmide-PEG4-C2-NH2 hydrochloride 是 E3 连接酶配体和linker组成的 偶联物,包含基于 PomalIDOmide 的 cereblon 配体和 4 个单元 PEG 的 linker,可用于 PROTAC 分子的合成。
产品描述
Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].
Cas No.
2357105-92-9
分子式
C23H33ClN4O8
分子量
528.98
别名
Pomalidomide-PEG4-C2-NH2 hydrochloride
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years