p38α inhibitor 2 is a highly potent and selective p38α MAPK inhibitor, with a pIC50 of 9.6. p38α inhibitor 2 inhibits the hERG ion channel (IC50=27 μM) and shows a promising selectivity profile when tested in a panel of 51 other protein kinases (<30% inhibition at 10 μM concentration) and a panel of 141 other biological targets[1].

1095003-80-7

C27H33N5O3

475.593

p38α inhibitor 2

DMSO:250 mg/mL (525.67 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years