Axl-IN-8 (NO.1) 是一种有效的AXL抑制剂，其IC50低于 1 nM。Axl-IN-8 也抑制c-MET，IC50在 1-10 nM 之间。Axl-IN-8 对 BaF3/TEL-AXL、MKN45 和 EBC-1 细胞均有抗增殖活性，其IC50值分别为<10、226.6 和 120.3 nM。

Axl-IN-8 (NO.1) is a potent AXL inhibitor, with an IC 50 of<1 nM. Axl-IN-8 also inhibits c-MET, with an IC 50 of 1-10 nM. Axl-IN-8 shows anti-proliferative activity against BaF3/TEL-AXL, MKN45, and EBC-1 cells, with IC 50 values of<10, 226.6 and 120.3 nM, respectively [1].

2231424-62-5

C31H29FN6O3

552.6

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years