BPN-15477 是一种剪接调节剂化合物 (SMC)，可恢复 ELP1 外显子 20 的正确剪接。它可用作于额颞叶痴呆研究。 BPN-15477 纠正了 ELP1 转录本的剪接，显着提高了体内所有组织（包括大脑）中功能蛋白的水平。

BPN-15477 is a splicing modulator compound (SMC) that restores the correct splicing of ELP1 exon 20. It can be used for frontotemporal dementia research. BPN-15477 corrects the splicing of the ELP1 transcript which significantly increases the level of functional protein in vivo in all tissues, including the brain [1].

1971086-99-3

C12H10ClN5

259.69

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years