DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).

In a rat model of obesity and impaired glucose tolerance, DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading and significantly suppresses hyperglycemia (0.3 mg/kg). The effect is based on its inhibitory effect on plasma DPP-IV activity.

625110-37-4

C11H18FN3O2

243.28

DPP-IV-IN-1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years