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Concanamycin B
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Concanamycin B图片
CAS NO:81552-33-2
包装:1 mg
市场价:13262元

产品介绍

产品描述

Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone resorption and maturation of CD8 T lymphocytes. It also prevents processing of major histocompatibility complex (MHC) class II precursors in human B cells, inhibiting the expression of MHC class II molecules on the cell surface.

Cas No.

81552-33-2

分子式

C45H73NO14

分子量

852.06

别名

Concanamycin B

储存和溶解度

Ethanol:Soluble
Methanol:Soluble
DMSO:Soluble
DMF:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years