ZIKV-IN-5 (化合物 5c) 是一种低细胞毒性的和酸稳定性的抗ZIKV剂 (EC50=0.71 μM)。ZIKV-IN-5 能有效抑制ZIKV NS5 MTase活性。

ZIKV-IN-5 (compound 5c) is a low-cytotoxicity and acid-stable anti- ZIKV agent ( EC 50 =0.71 μM). ZIKV-IN-5 effectively inhibits the activity of ZIKV NS5 MTase [1].

ZIKV-IN-5 (0-200 μM; 96 h) shows low cytotoxicity [1]. Cell Cytotoxicity Assay [1] Cell Line: Vero cells Concentration: 0-200 μM Incubation Time: 96 h Result: Exhibited low cytotoxicities with a CC 50 value of more than 200 μM

C36H45NO4Si

583.83

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years