Polygodial 是一种抗真菌增效剂和抗生素。它是一种倍半萜，具有抗痛觉过敏的作用。

Polygodial is an antifungal potentiator and an antibiotic, particularly against Saccharomyces cerevisiae, Candida utilis, and Sclerotinia libertiana.

When tested on S. cerevisiae, polygodial proved to be fungicidal rather than fungistatic. When the cells of S. cerevisiae are treated in vitro with polygodial for 10 min, the cell membrane becomes severely damaged, and many vesicles, possibly formed from the fragmented cell membrane, can be observed within the cytoplasm[1].

Polygodial (0.1 to 10 mg kg(-1), i.p.) produced significant inhibition of acetic acid, kaolin and zymosan-induced writhing in mice, being about 14 to 27-fold more potent than the hydroalcoholic extract at the ID50 level[2].

6754-20-7

C15H22O2

234.33

Tadeonal;水蓼二醛;Polygodial

DMSO:65 mg/ml (277.39 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years