产品描述
Pentosan Polysulfate Sodium is a potent and selective anti-HIV agent.with anti-inflammatory and pro-chondrogenic properties,and used for treatment of interstitial cystitis.
体外活性
Pentosan Polysulfate Sodium suppresses NF-κB, decreases the proinflammatory actions of TNFα, and decreases high glucose and advanced glycation end products (AGEs) stimulated MCP-1 production[3].
体内活性
Pentosan Polysulfate Sodium treatment preserves renal function, significantly reduces albuminuria, and markedly decreases the severity of renal lesions, including tubulointerstitial inflammation. Pentosan Polysulfate Sodium also reduces upregulation of TNFα and proinflammatory genes in aging diabetic kidneys[3].
Cas No.
140207-93-8
别名
Pentosan Polysulfate Sodium;Pentosan Polysulfate Sodium (W/W 43%)
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years