Nourseothricin sulfate是广谱抗生素,可破坏革兰氏阴性菌的外膜,并且是Fonsecaea pedROSoi的主要选择性标记物。它抑制原核细胞中蛋白质的生物合成,并强烈抑制真核生物,还可作为多种生物的选择性标记物。
产品描述
Nourseothricin sulfate is a broad-spectrum antibiotic,and inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi .
体内活性
Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions.?Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin.?There is a high degree of accumulation of Nourseothricin in renal cortical slices.?In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation.?Age dependent differences in Nourseothricin accumulation does not exist[1].
Cas No.
96736-11-7
分子式
C50H94N20O22S
分子量
1359.48
别名
Streptothricin sulfate;链丝菌素硫酸盐;Nourseothricin sulfate
储存和溶解度
H2O:250 mg/mL (183.90 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years