VK-II-86 是一种非β-阻断卡维地洛类似物。它可以防止哇巴因诱导的心脏毒性。
产品描述
VK-II-86 is a non-β-blocking carvedilol analog. It prevents ouabain-Induced cardiotoxicity
体内活性
VK-II-86 are effective to prevent ouabain-induced apoptosis and spontaneous contractions indicative of arrhythmogenic activity without affecting inotropy and demonstrated to be effective in human models, thus emerging as a therapeutic tool for the prevention of digitalis-induced arrhythmias and cardiac toxicity[1].
Cas No.
955371-84-3
分子式
C25H28N2O4
分子量
420.509
别名
VK-II-86
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years