ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.

ARL67156 is not an effective inhibitor of NTPDase2, NTPDase8, NPP3 and ecto-5′-nucleotidase (CD73). And It also reduces the activity of these enzymes[1]. ARL67156 trisodium salt is also an effective inhibitor of UTP breakdown by superior cervical ganglion cells and to potentiate contractions elicited by this nucleotide in isolated tail artery of rat.

1021868-83-6

C15H24Br2N5Na3O12P3

788.08

ARL67156 trisodium salt

H2O:25 mg/mL (31.72 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years