NTPDase-IN-1 (化合物 5a) 是一种具有选择性的NTPDase抑制剂，其对h-NTPDase-1/-2/-8的IC50值分别为 0.05, 0.23 和 0.54 μM。NTPDase-IN-1 可非竞争性地抑制h-NTPDase-1/-2，其对h-NTPDase-1的Km值为 21 μM。NTPDase-IN-1 可用于癌症、免疫学疾病以及细菌感染的研究。

NTPDase-IN-1 (compound 5a) is a selective NTPDase inhibitor with IC 50 s of 0.05, 0.23 and 0.54 μM for h-NTPDase-1/-2/-8, respectively. NTPDase-IN-1 non-competitively inhibits h-NTPDase-1/-2 with a K m of 21 μM for h-NTPDase-1. NTPDase-IN-1 can be used in studies of cancer, immunologic disorders as well as bacterial infections [1].

C18H25N3OS2

363.54

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years