NTPDase-IN-2 (化合物 5g) 是一种具有选择性的NTPDase抑制剂,其对h-NTPDase-2/-8的IC50值分别为 0.04 和 2.27 μM。NTPDase-IN-2 可非竞争性地抑制h-NTPDase-1/-2,其对h-NTPDase-2的Km值为 74 μM。NTPDase-IN-2 可用于癌症、免疫学疾病以及细菌感染的研究。
产品描述
NTPDase-IN-2 (compound 5g) is a selective NTPDase inhibitor with IC 50 s of 0.04 and 2.27 μM for h-NTPDase-2/-8, respectively. NTPDase-IN-2 non-competitively inhibits h-NTPDase-1/-2 with a K m of 74 μM for h-NTPDase-2. NTPDase-IN-2 can be used in studies of cancer, immunologic disorders as well as bacterial infections [1].
分子式
C24H20FN3OS2
分子量
449.56
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years