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Sofiniclin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sofiniclin图片
CAS NO:799279-80-4
包装:10 mg
市场价:11937元

产品名称
ABT 894
产品介绍

产品描述

Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).

体外活性

Sofiniclin is more potent than ABT-089 at both receptor subtypes, with Ki values of 1.3 nM for 125I-epibatidine binding and of 1.9 nM for 125I-α-conotoxinMII binding [1].

体内活性

Compared to vehicle monkey, Sofiniclin (0.001 to 0.10 mg/kg, p.o.) produces significant reductions in LIDs [1]. Sofiniclin (0.1 mg/kg) does not decrease LIDs in monkeys with severe nigrostriatal damage [2].

Cas No.

799279-80-4

分子式

C10H11Cl2N3

分子量

244.12

别名

ABT 894;Sofiniclin

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years