(Rac)-BL-918 是BL-918 的消旋体。BL-918 是一种 UNC-51 样激酶 1 的有效激活剂,EC50 为 24.14 nM。可诱导细胞保护性自噬以治疗帕金森病。
产品描述
(Rac)-BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinson’s disease treatment [1].
Cas No.
2435589-07-2
分子式
C23H15F8N3OS
分子量
533.44
别名
(Rac)-BL-918
储存和溶解度
DMSO:125 mg/mL (234.33 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years