Benzethonium chloride 是合成季铵盐，具有表面活性剂、防腐剂和广谱抗菌特性。它作用于在爪蟾卵母细胞，抑制人重组α7和α4β2神经元烟碱性乙酰胆碱受体。

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.

携带人咽鳞癌细胞肿瘤SCID小鼠体内, Benzethonium chloride（5 mg/kg）抑制移植瘤的生长.

在人咽鳞癌细胞中,Benzethonium chloride（9 μM）12小时后会诱导细胞凋亡,并且激活胱天蛋白酶。Benzethonium（5 μM）增强葡萄糖消耗对细胞溶质Ca(2+)浓度和膜联蛋白结合的影响。

Cells are seeded in 96-well plates at 5,000 per well in 100 μL of growth medium and allowed to incubate for 24 hours. Benzethonium chloride is then added, as indicated, in a total volume of 5 μL. After 48 hours, MTS assay is done according to the specifications of the manufacturer, with DMSO (0.1%)–treated cells as negative control and cisplatin (166.6 μM)–treated cells as positive control.(Only for Reference)

121-54-0

C27H42ClNO2

448.09

Phemeride;苄索氯铵;Hyamine;Quatrachlor;Benzethonium chloride

H2O:83 mg/mL (185.2 mM)
DMSO:22.4 mg/mL (49.99 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years