SOS1-IN-5 是一种有效的SOS1抑制剂。SOS1-IN-5 是嘧啶双环衍生物。SOS1-IN-5通过干扰Ras-SOS1相互作用阻断KRas的激活，达到广谱抑制KRas活性的目的。SOS1-IN-5具有研究癌症疾病的潜力(信息提取自专利 WO2021203768A1，compound 4)。

SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4) [1].

2716956-47-5

C26H31F3N4O5

536.54

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years