KRAS G12C inhibitor 25 是KRAS G12C抑制剂。KRAS G12C inhibitor 25 抑制 KRAS-G12C 突变体的 SOS1 辅助的 GDP/GTP 交换活性 (IC50=0.48 nM)。详细信息请参加专利 WO2021216770A1 compound 3。

KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC 50 =0.48 nM). From WO2021216770A1 compound 3 [1].

2734060-73-0

C32H41N7O2

555.71

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years