Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. It has been reported to inhibit U87MG cells with an IC50 value of 2.8 μg/ml and demonstrates cytostatic activity specifically against glioblastoma cells without affecting normal cells. It also displays antiproliferative activity against melanoma, breast, and lung cancer cells in vitro at 100 μg/ml.

15664-29-6

C35H36N4O5

592.696

Pheophorbide a

DMF:1 mg/mL
DMSO:1 mg/mL
DMSO:PBS(pH 7.2) (1:3):0.25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years