BVT14225 是一种选择性的11β羟基类固醇脱氢酶1型(11β-HSD1)抑制剂(IC50:52 nM)。

BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).

BVT-14225 shows high activity in the enzyme assay with 90% inhibition at 10 μM. It has an IC50 for 11β-HSD1 on a human enzyme assay of 52 nM.

376638-65-2

C16H20ClN3O3S2

401.93

BVT 14225;BVT-14225

DMSO:27 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years