AKR1C3-IN-8 (Compound 5) 是一种有效的、选择性的AKR1C3抑制剂，IC50为 0.069 μM。AKR1C3-IN-8 具有抗肿瘤活性。

AKR1C3-IN-8 (Compound 5) is a potent, selective AKR1C3 inhibitor with an IC 50 of 0.069 μM. AKR1C3-IN-8 shows antitumor activity [1].

AKR1C3-IN-8 (Compound 5) shows antiproliferative activity with an IC 50 of 52.06 ± 0.99 μM against prostate cancer cell line 22rv1 [1]. AKR1C3-IN-8 (0-50 μM) inhibits PSA expression and testosterone production on 22RV1 cells [1].

C23H20N4O3

400.43

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years