AKR1C3-IN-6 (Compound 1) 是一种有效的、选择性的AKR1C3抑制剂，对 AKR1C3 和AKR1C2的IC50分别为 0.31 μM 和 73.23 μM。AKR1C3-IN-6 具有抗肿瘤活性。

AKR1C3-IN-6 (Compound 1) is a potent, selective AKR1C3 inhibitor with IC 50 values of 0.31 μM and 73.23 μM against AKR1C3 and AKR1C2, respectively. AKR1C3-IN-6 shows antitumor activity [1].

AKR1C3-IN-6 (Compound 1) shows antiproliferative activity with an IC 50 of 81.40 ± 2.29 μM against prostate cancer cell line 22rv1 [1].

2137881-54-8

C18H15F3N4O3

392.33

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years