MLS0315771 是来源于磷酸甘露糖异构酶的竞争性抑制剂， 其IC50值为~1 μM，Ki=为 1.4 μM。

MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).

MLS0315771 is toxic to the zebrafish embryos above 2 μM. MLS0315771 toxicity at higher concentrations is an off-target effect. MLS0315771 enhances mannose flux toward glycosylation. It ~50% of embryos appeared sick within 20 min at 8-10 μM, and most of them die by 30-60 min.

727664-91-7

C15H12FNOS

273.33

MLS0315771

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years