Steroid sulfatase-IN-1 是一种有效的且具有口服活性的Steroid sulfatase抑制剂，IC50为 1.71 μM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用 (TGI=51%)。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC 50 of 1.71 μM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer [1].

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51% [1]. Animal Model: 67NR mouse [1] Dosage: 50 mg/kg Administration: P.o. Result: Showed significant antitumor activity with the TGI value of 51%.

2403716-19-6

C14H10Cl2N4O3S

385.23

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years