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LYG-202
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LYG-202图片
CAS NO:1175077-25-4
包装:50 mg
市场价:8238元

产品介绍

产品描述

LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities. It inhibits proliferation of HepG2, MCF-7, HeLa, BGC-823, MDA-MB-435, and HCT116 cancer cells in vitro (IC50s = 4.74-27.70 μM) via induction of apoptosis and dissipation of the mitochondrial membrane potential. LYG-202 reduces tumor growth in S180 sarcoma cell-inoculated mice. It also inhibits VEGF-stimulated human umbilical vein endothelial cells (HUVEC) cell migration and tube formation in vitro and decreases capillary sprouting in isolated rat aortic rings and the chicken chorioallantoic membrane (CAM) model of angiogenesis.

Cas No.

1175077-25-4

分子式

C25H30N2O5

分子量

438.52

别名

LYG-202

储存和溶解度

DMF:PBS (pH7.2) (1:40):0.12 mg/mL
DMF:14 mg/mL
Ethanol:2.5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years