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KYP-2047
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KYP-2047图片
CAS NO:796874-99-2
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品介绍
KYP-2047 是一种非常有效的选择性脯氨酰寡肽酶 (POP) 抑制剂。

产品描述

KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.

体外活性

In cell lines, oxidative stress induced a robust aggregation of α-synuclein,and low concentrations of KYP-2047 significantly reduced the number of cells with α-synuclein inclusions while abolishing the colocalization of α-synuclein and PREP. KYP-2047 significantly reduced the amount of aggregated α-synuclein,and it had beneficial effects on cell viability.?In the transgenic mice, a 5-day treatment with the PREP inhibitor reduced the amount of α-synuclein immunoreactivity and soluble α-synuclein protein in the brain[1].

Cas No.

796874-99-2

分子式

C20H25N3O2

分子量

339.439

别名

KYP-2047

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years