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LSD1-IN-21
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
LSD1-IN-21 (化合物 5a) 是一种有效的可透过血脑屏障的LSD1(赖氨酸特异性去甲基化酶 -1) 抑制剂,其IC50为 0.956 μM。LSD1-IN-21 显著降低促炎细胞因子TNF-α。LSD1-IN-21 具有良好的抗癌和抗炎活性。

产品描述

LSD1-IN-21 (compound 5a) is a potent and BBB-penetrated LSD1 (Lysine specific demethylase-1) inhibitor, with an IC 50 of 0.956 μM. LSD1-IN-21 significantly reduces the pro-inflammatory cytokine TNF-α. LSD1-IN-21 shows good anticancer and anti-inflammatory activity [1].

体外活性

LSD1-IN-21 (compound 5a) shows potent anti-cancer activity with GI 50 values of 0.414 and 0.417 μM against HOP-62 and OVCAR-4 cell lines, respectively [1].

分子式

C24H25N5O2S

分子量

447.55

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years