IDO1/2-IN-1 是第一个有效的IDO1/IDO2双重抑制剂，对 IDO1 和 IDO2 的IC50分别为 28 nM 和 144 nM。IDO1/2-IN-1 具有抗肿瘤活性。具有口服活性。

IDO1/2-IN-1 (compound 4t) is the first potent IDO1/IDO2 dual inhibitor with IC 50 s of 28 nM and 144 nM for IDO1 and IDO2, respectively. IDO1/2-IN-1 exhibits antitumor activies. Orally active [1].

2310286-45-2

C16H18BrFN8O4

485.27

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years