Pravastatin lactone is a metabolite of pravastatin , a hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor that is a ring-hydroxylated metabolite of mevastatin . Pravastatin lactone is formed when pravastatin undergoes acid-catalyzed non-enzymatic lactonization in the stomach following oral administration.

85956-22-5

C23H34O6

406.51

Pravastatin lactone

DMSO:20 mg/mL
DMF:25 mg/mL
PBS (pH 7.2):10 mg/mL
Ethanol:12.5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years