CYP17-IN-1 是一种有效的 CYP17 口服抑制剂，可抑制大鼠和人类的 CYP17，IC50 分别为 15.8 和 20.1 nM。

CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.

The IC50 value of CYP17-IN-1 for CYP3A4 is 8.5 μM[1].

CYP17-IN-1 dose-dependently reduced plasma testosterone levels in Sprague-Dawley rats[1].

2093317-51-0

C18H17FN2S

312.4

CYP17-IN-1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years