Cholesterol 24-Hydroxylase-IN-1 (compound 17) 是一种强效、口服活性和高选择性的胆固醇24-羟化酶(CH24H or CYP46A1)抑制剂 (IC50=8.5 nM)。Cholesterol 24-Hydroxylase-IN-1 能透过血脑屏障。

Cholesterol 24-hydroxylase-IN-1 (compound 17) is a potent, orally active, and highly selective cholesterol 24-hydroxylase (CH24H or CYP46A1) inhibitor ( IC 50 =8.5 nM). Cholesterol 24-hydroxylase-IN-1 can cross blood-brain barrier [1].

1613480-70-8

C17H23N5O

313.4

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years