AN2718 是一种苯并恶硼烷化合物，通过 OBORT 机制抑制蛋白质合成，有抗真菌功效。

AN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM for A. fumigatus and C. albicans LeuRS, respectively), blocking protein synthesis.

AN2718 inhibits leucyl-tRN/A synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 μM for A. fumigatus and C. albicans LeuRS, respectively)

174672-06-1

C7H6BClO2

168.4

AN2718

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years