CAXII-IN-1 (Compound 17) 是一种选择性的CA XII抑制剂,对hCA XII和hCA IX的Ki值分别为 3.8 nM 和 56.0 nM。CAXII-IN-1 具有抗肿瘤活性。
产品描述
CAXII-IN-1 (Compound 17) is a selective CA XII inhibitor with K i values of 3.8 nM and 56.0 nM against hCA XII and hCA IX, respectively. CAXII-IN-1 shows antitumor activity [1].
体外活性
CAXII-IN-1 (Compound 17) shows cytotoxicity with IC 50 values of 20±1, 4.8±0.03 and 14±2 μM against MCF-7, HeLa and A549 cells, respectively [1].
Cas No.
2479918-59-5
分子式
C13H7Cl2NO3S
分子量
328.17
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years