FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s =<0.003-1.9 μg/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.

144371-88-0

C51H82N8O21S

1175.3

FR901379

Methanol:Slightly soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years