Splenopentin diacetate 是一种合成的免疫调节肽,可以再现脾和胸腺激素胸腺生成素的生物活性。
产品描述
Splenopentin diacetate is a synthetic immunomodulating peptide and can reproduce the biological activities of splenin and thymic hormone thymopoietin.
体外活性
Splenopentin diacetate (0.1 ng/mL-10 μg/mL) induces phenotypic differentiation of both T- and B-cell precursor cells, to increase the number of antibody-forming cells in mice after gamma irradiation[2].
体内活性
Splenopentin diacetate (0.01-100 μg; i.p.) has no demonstrable effect on neuromuscular transmission of mice[2]. Splenopentin diacetate (1 mg/kg; i.p.) accelerates Langerhans cell recruitment and leads to pretreatment levels of Langerhans cell (LC) density in the skin of female Balb/c/Bln mice were injected Cyclophosphamide or Dexamethasone[3].
Cas No.
105184-37-0
分子式
C33H55N9O11
分子量
753.84
别名
Splenin pentapeptide (32-36);醋酸脾脏五肽;Splenopentin Acetate;SP5;Arg-lys-glu-val-tyr;Thymopoietin III pentapeptide (32-36);Splenopentin diacetate
储存和溶解度
H2O:Insoluble
DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years