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COX-2-IN-23
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2417995-08-3
包装与价格:
包装价格(元)
5 mg电议
50 mg电议
100 mg电议

产品介绍
COX-2-IN-23 (compound 9a) 是一种选择性的COX-2抑制剂,COX-2 和 COX-1 的IC50值分别为 0.28 和 20.14 μM。COX-2-IN-23 具有抗炎活性和低致溃疡活性。

产品描述

COX-2-IN-23 (compound 9a) is a selective COX-2 inhibitor with IC 50 values of 0.28 and 20.14 μM for COX-2 and COX-1. COX-2-IN-23 has anti-inflammatory activity and low ulcerogenic activity.

体内活性

COX-2-IN-23 (compound 9a) (9 mg/kg; a single i.p.; 0-4 hours) exhibits anti-inflammatory activities and lowest incidence of pepticulcer [1]. Animal Model: Mature male albino rats [1] Dosage: 9 mg/kg Administration: Intraperitoneal injection; 0, 1, 2, 3 and 4 hours. Result: Had similar ulcerogenic activity to celecoxib.

Cas No.

2417995-08-3

分子式

C24H25N5O3S2

分子量

495.62

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years