SB399885 HCl 是一种有效的脑渗透剂和口服活性 SR-6 拮抗剂。它对 SR-6 的选择性比其他血清素受体高 200 倍（对人重组、天然大鼠和天然人 SR-6 受体的 pKi：分别为 9.11、8.81 和 9.02）。

SB 399885 hydrochloride is an effective, brain penetrant, and orally active antagonist of SR-6. It shows 200-fold selectivity for SR-6 over other serotonin receptors (pKi: 9.11, 8.81, and 9.02 for human recombinant, native rat, and native human SR-6 receptors, respectively).

402713-80-8

C18H21Cl2N3O4S

446.35

SB 399885;SB399885 Hydrochloride;SB-399885;SB399885;SB399885 HCl

DMSO:55 mg/ml (123.22 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years